Exosomes: Potential Therapies for Disease via Regulating TLRs
Joint Authors
Wang, Mingshu
Jia, Renyong
Cheng, Anchun
Yin, Zhongqiong
Guo, Hong-Yan
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Exosomes are small membrane vesicles that retain various substances such as proteins, nucleic acids, and small RNAs.
Exosomes play crucial roles in many physiological and pathological processes, including innate immunity.
Innate immunity is an important process that protects the organism through activating pattern recognition receptors (PRRs), which then can induce inflammatory factors to resist pathogen invasion.
Toll-like receptor (TLR) is one member of PRRs and is important in pathogen clearance and nervous disease development.
Although exosomes and TLRs are two independent materials, abundant evidences imply exosomes can regulate innate immunity through integrating with TLRs.
Herein, we review the most recent data regarding exosome regulation of TLR pathways.
Specifically, exosome-containing materials can regulate TLR pathways through the interaction with TLRs.
This is a new strategy regulating immunity to resist pathogens and therapy diseases, which provide a potential method to cure diseases.
American Psychological Association (APA)
Guo, Hong-Yan& Cheng, Anchun& Wang, Mingshu& Yin, Zhongqiong& Jia, Renyong. 2020. Exosomes: Potential Therapies for Disease via Regulating TLRs. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1191571
Modern Language Association (MLA)
Guo, Hong-Yan…[et al.]. Exosomes: Potential Therapies for Disease via Regulating TLRs. Mediators of Inflammation No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1191571
American Medical Association (AMA)
Guo, Hong-Yan& Cheng, Anchun& Wang, Mingshu& Yin, Zhongqiong& Jia, Renyong. Exosomes: Potential Therapies for Disease via Regulating TLRs. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1191571
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191571