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The Functional Roles of IL-33ST2 Axis in Ocular Diseases
Joint Authors
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-18
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Interleukin-33 (IL-33), an important member of the IL-1 family, plays a pivotal role in regulating immune responses via combining with its receptor suppression of tumorigenicity 2 (ST2).
We have already known IL-33/ST2 axis participates in the pathogenesis of various diseases, including liver diseases, renal diseases, and neurological diseases.
Recently, emerging studies are indicating that IL-33/ST2 is also involved in a wide range of ocular diseases, such as allergic eye disease, keratitis and corneal regeneration, dry eye disease, uveitis, vitreoretinal diseases, and neuromyelitis optica spectrum disorder.
In this review, we will summarize and discuss the current understanding about the functional roles of IL-33/ST2 in eyes, with an attempt to explore the possible study perspectives and therapeutic alternatives in the future.
American Psychological Association (APA)
Qian, Yujing& Zhang, Meifen. 2020. The Functional Roles of IL-33ST2 Axis in Ocular Diseases. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1191804
Modern Language Association (MLA)
Qian, Yujing& Zhang, Meifen. The Functional Roles of IL-33ST2 Axis in Ocular Diseases. Mediators of Inflammation No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1191804
American Medical Association (AMA)
Qian, Yujing& Zhang, Meifen. The Functional Roles of IL-33ST2 Axis in Ocular Diseases. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1191804
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191804