Immunophenotypic Profiles in Polycystic Ovary Syndrome
Joint Authors
Hu, Cong
Pang, Bo
Ma, Zhanchuan
Yi, Huanfa
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Polycystic ovary syndrome (PCOS) a long-known endocrinopathy and one of the most common endocrine-reproductive-metabolic disorders in women, which can lead to infertility.
Although the precise etiology remains unclear, PCOS is considered as a complex genetic trait, with a high degree of heterogeneity.
Besides, hormones and immune cells, including both innate and adaptive immune cells, are reportedly a cross talk in PCOS.
Chronic low-grade inflammation increases autoimmune disease risk.
This proinflammatory condition may, in turn, affect vital physiological processes that ultimately cause infertility, such as ovulation failure and embryo implantation.
Here, we review the accumulating evidence linking PCOS with inflammatory status providing an overview of the underlying hormone-mediated dysregulation of immune cells.
We mainly focus on the correlational evidence of associations between immune status in women and the increased prevalence of PCOS, along with the specific changes in immune responses.
Further recognition and exploration of these interactions may help elucidate PCOS pathophysiology and highlight targets for its treatment and prevention.
American Psychological Association (APA)
Hu, Cong& Pang, Bo& Ma, Zhanchuan& Yi, Huanfa. 2020. Immunophenotypic Profiles in Polycystic Ovary Syndrome. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1191847
Modern Language Association (MLA)
Hu, Cong…[et al.]. Immunophenotypic Profiles in Polycystic Ovary Syndrome. Mediators of Inflammation No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1191847
American Medical Association (AMA)
Hu, Cong& Pang, Bo& Ma, Zhanchuan& Yi, Huanfa. Immunophenotypic Profiles in Polycystic Ovary Syndrome. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1191847
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191847