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Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals
Joint Authors
Lee, Bonggi
Moon, Kyoung Mi
Kim, Choon Young
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-16
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The intestine plays an essential role in integrating immunity and nutrient digestion and absorption.
Adjacent intestinal epithelia form tight junctions (TJs) that are essential to the function of the physical intestinal barrier, regulating the paracellular movement of various substances including ions, solutes, and water across the intestinal epithelium.
Studies have shown that TJ dysfunction is highly associated with metabolic and inflammatory diseases.
Thus, molecular and nutritional factors that improve TJ activity have gained attention in the pharmaceutical and medicinal fields.
This review focuses on the association between TJ and diverse pathological conditions, as well as various molecular and nutritional interventions designed to boost TJ integrity.
American Psychological Association (APA)
Lee, Bonggi& Moon, Kyoung Mi& Kim, Choon Young. 2018. Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1191919
Modern Language Association (MLA)
Lee, Bonggi…[et al.]. Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals. Journal of Immunology Research No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1191919
American Medical Association (AMA)
Lee, Bonggi& Moon, Kyoung Mi& Kim, Choon Young. Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1191919
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1191919