Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica
Joint Authors
Luria-Pérez, Rosendo
Hernández-Luna, Marco Antonio
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-13
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
In recent years, cancer immunotherapy has undergone great advances because of our understanding of the immune response and the mechanisms through which tumor cells evade it.
A century after the first immunotherapy attempt based on bacterial products described by William Coley, the use of live attenuated bacterial vectors has become a promising alternative in the fight against cancer.
This review describes the role of live attenuated Salmonella enterica as an oncolytic and immunotherapeutic agent, due to its high affinity for tumor tissue and its ability to activate innate and adaptive antitumor immune response.
Furthermore, its potential use as delivery system of tumor antigens and immunomodulatory molecules that induce tumor regression is also reviewed.
American Psychological Association (APA)
Hernández-Luna, Marco Antonio& Luria-Pérez, Rosendo. 2018. Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1192023
Modern Language Association (MLA)
Hernández-Luna, Marco Antonio& Luria-Pérez, Rosendo. Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica. Journal of Immunology Research No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1192023
American Medical Association (AMA)
Hernández-Luna, Marco Antonio& Luria-Pérez, Rosendo. Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1192023
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192023