Essential Oil and Juice from Bergamot and Sweet Orange Improve Acne Vulgaris Caused by Excessive Androgen Secretion

Joint Authors

Sun, Peng
Wang, Chengtao
Zhao, Liang
Zhang, Nanhai
Mehmood, Arshad
Zhang, Liebing
Ji, Baoping
Zhou, Feng
Wu, Wei

Source

Mediators of Inflammation

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-10-06

Country of Publication

Egypt

No. of Pages

10

Main Subjects

Diseases

Abstract EN

Acne vulgaris is one of the most common chronic inflammatory skin diseases.

Bergamot and sweet orange are rich in nutritional and functional components, which exhibit antioxidant, anti-inflammatory, and antiapoptotic effect.

The aim of this study was to evaluate the potential effect of bergamot and sweet orange (juice and essential oil) on acne vulgaris caused by excessive secretion of androgen.

Eighty male golden hamsters were randomly divided into 10 groups and received low or high dose of bergamot and sweet orange juice and essential oil, physiological saline, and positive drugs for four weeks, respectively.

Results showed that all interventions could improve acne vulgaris by reducing the growth rate of sebaceous gland spots, inhibiting TG accumulation, decreasing the release of inflammatory cytokines (notably reducing IL-1α levels), promoting apoptosis in the sebaceous gland, and decreasing the ratio of T/E2.

Among them, bergamot and orange essential oil may have better effects (dose dependent) on alleviating acne vulgaris than the corresponding juice.

In view of the large population of acne patients and the widespread use of sweet orange and bergamot, this study is likely to exert an extensive and far-reaching influence.

American Psychological Association (APA)

Sun, Peng& Zhao, Liang& Zhang, Nanhai& Wang, Chengtao& Wu, Wei& Mehmood, Arshad…[et al.]. 2020. Essential Oil and Juice from Bergamot and Sweet Orange Improve Acne Vulgaris Caused by Excessive Androgen Secretion. Mediators of Inflammation،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1192162

Modern Language Association (MLA)

Sun, Peng…[et al.]. Essential Oil and Juice from Bergamot and Sweet Orange Improve Acne Vulgaris Caused by Excessive Androgen Secretion. Mediators of Inflammation No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1192162

American Medical Association (AMA)

Sun, Peng& Zhao, Liang& Zhang, Nanhai& Wang, Chengtao& Wu, Wei& Mehmood, Arshad…[et al.]. Essential Oil and Juice from Bergamot and Sweet Orange Improve Acne Vulgaris Caused by Excessive Androgen Secretion. Mediators of Inflammation. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1192162

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1192162