Innate Lymphoid Cells: A Link between the Nervous System and Microbiota in Intestinal Networks
Joint Authors
Zhao, Linhua
Tong, Xiaolin
Di, Sha
Han, Lin
Gao, Zezheng
Wang, Qing
Wang, Xinmiao
Wu, Haoran
Li, Qingwei
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-20
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Innate lymphoid cells (ILCs) are a novel family of innate immune cells that act as key coordinators of intestinal mucosal surface immune defense and are essential for maintaining intestinal homeostasis and barrier integrity by responding to locally produced effector cytokines or direct recognition of exogenous or endogenous danger patterns.
ILCs are also involved in the pathogenesis of inflammatory bowel disease (IBD).
Many studies have demonstrated the occurrence of crosstalk between ILCs and intestinal microbiota, and ILCs have recently been shown to be connected to the enteric nervous system (ENS).
Thus, ILCs may act as a key link between the nervous system and microbiota in intestinal networks.
In this review, we briefly summarize the role of the ILCs in the intestinal tract (particularly in the context of IBD) and discuss the relationship between ILCs and the microbiota/ENS.
American Psychological Association (APA)
Han, Lin& Wang, Xinmiao& Di, Sha& Gao, Zezheng& Li, Qingwei& Wu, Haoran…[et al.]. 2019. Innate Lymphoid Cells: A Link between the Nervous System and Microbiota in Intestinal Networks. Mediators of Inflammation،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1192663
Modern Language Association (MLA)
Han, Lin…[et al.]. Innate Lymphoid Cells: A Link between the Nervous System and Microbiota in Intestinal Networks. Mediators of Inflammation No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1192663
American Medical Association (AMA)
Han, Lin& Wang, Xinmiao& Di, Sha& Gao, Zezheng& Li, Qingwei& Wu, Haoran…[et al.]. Innate Lymphoid Cells: A Link between the Nervous System and Microbiota in Intestinal Networks. Mediators of Inflammation. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1192663
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192663