Biological Properties and the Role of IL-25 in Disease Pathogenesis
Joint Authors
Bie, Qingli
Zhang, Bin
Shangguan, Guo-Qiang
Liu, Yuwan
Shao, Zewei
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The interleukin- (IL-) 17 superfamily, a T cell-derived cytokine, consists of 6 ligands (IL-17A–IL-17F) and 5 receptors (IL-17RA–IL-17RE).
IL-17A, a prototype member of this family, is involved in the pathogenesis of allergies, autoimmune diseases, allograft transplantations, and malignancies.
By contrast, IL-17B is reported to be closely related to certain diseases, particularly tumors such as breast cancer, gastric cancer, and pancreatic cancer.
Recently, the biological function of IL-17E (also called IL-25) in disease, particularly airway diseases, has attracted the attention of researchers.
However, studies on IL-25 are scant.
In this review, we detail the structural characteristics, expression patterns, responder cells, biological properties, and role of IL-25 in disease pathogenesis.
American Psychological Association (APA)
Liu, Yuwan& Shao, Zewei& Shangguan, Guo-Qiang& Bie, Qingli& Zhang, Bin. 2018. Biological Properties and the Role of IL-25 in Disease Pathogenesis. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1192792
Modern Language Association (MLA)
Liu, Yuwan…[et al.]. Biological Properties and the Role of IL-25 in Disease Pathogenesis. Journal of Immunology Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1192792
American Medical Association (AMA)
Liu, Yuwan& Shao, Zewei& Shangguan, Guo-Qiang& Bie, Qingli& Zhang, Bin. Biological Properties and the Role of IL-25 in Disease Pathogenesis. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1192792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192792