Roles of Macrophage Subtypes in Bowel Anastomotic Healing and Anastomotic Leakage
Joint Authors
Wu, Zhouqiao
Ji, Jiafu
Shi, Jinyao
Li, Ziyu
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Macrophages play an important role in host defense, in addition to the powerful ability to phagocytose pathogens or foreign matters.
They fulfill a variety of roles in immune regulation, wound healing, and tissue homeostasis preservation.
Macrophages are characterized by high heterogeneity, which can polarize into at least two major extremes, M1-type macrophages (classical activation) which are normally derived from monocytes and M2-type macrophages (alternative activation) which are mostly those tissue-resident macrophages.
Based on the wound healing process in skin, the previous studies have documented how these different subtypes of macrophages participate in tissue repair and remodeling, while the mechanism of macrophages in bowel anastomotic healing has not yet been established.
This review summarizes the currently available evidence regarding the different roles of polarized macrophages in the physiological course of anastomotic healing and their pathological roles in anastomotic leakage, the most dangerous complication after gastrointestinal surgery.
American Psychological Association (APA)
Shi, Jinyao& Wu, Zhouqiao& Li, Ziyu& Ji, Jiafu. 2018. Roles of Macrophage Subtypes in Bowel Anastomotic Healing and Anastomotic Leakage. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1192876
Modern Language Association (MLA)
Shi, Jinyao…[et al.]. Roles of Macrophage Subtypes in Bowel Anastomotic Healing and Anastomotic Leakage. Journal of Immunology Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1192876
American Medical Association (AMA)
Shi, Jinyao& Wu, Zhouqiao& Li, Ziyu& Ji, Jiafu. Roles of Macrophage Subtypes in Bowel Anastomotic Healing and Anastomotic Leakage. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1192876
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192876