The Role of Zinc and Zinc Homeostasis in Macrophage Function
Joint Authors
Gao, Hong
Dai, Wei
Zhao, Lu
Min, Junxia
Wang, Fudi
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-06
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Zinc has long been recognized as an essential trace element, playing roles in the growth and development of all living organisms.
In recent decades, zinc homeostasis was also found to be important for the innate immune system, especially for maintaining the function of macrophages.
It is now generally accepted that dysregulated zinc homeostasis in macrophages causes impaired phagocytosis and an abnormal inflammatory response.
However, many questions remain with respect to the mechanisms that underlie these processes, particularly at the cellular and molecular levels.
Here, we review our current understanding of the roles that zinc and zinc transporters play in regulating macrophage function.
American Psychological Association (APA)
Gao, Hong& Dai, Wei& Zhao, Lu& Min, Junxia& Wang, Fudi. 2018. The Role of Zinc and Zinc Homeostasis in Macrophage Function. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1192878
Modern Language Association (MLA)
Gao, Hong…[et al.]. The Role of Zinc and Zinc Homeostasis in Macrophage Function. Journal of Immunology Research No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1192878
American Medical Association (AMA)
Gao, Hong& Dai, Wei& Zhao, Lu& Min, Junxia& Wang, Fudi. The Role of Zinc and Zinc Homeostasis in Macrophage Function. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1192878
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192878