Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus
Joint Authors
Vadnie, Chelsea A.
McClung, Colleen A.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-28, 28 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-05
Country of Publication
Egypt
No. of Pages
28
Main Subjects
Abstract EN
Circadian rhythm disturbances are a common symptom among individuals with mood disorders.
The suprachiasmatic nucleus (SCN), in the ventral part of the anterior hypothalamus, orchestrates physiological and behavioral circadian rhythms.
The SCN consists of self-sustaining oscillators and receives photic and nonphotic cues, which entrain the SCN to the external environment.
In turn, through synaptic and hormonal mechanisms, the SCN can drive and synchronize circadian rhythms in extra-SCN brain regions and peripheral tissues.
Thus, genetic or environmental perturbations of SCN rhythms could disrupt brain regions more closely related to mood regulation and cause mood disturbances.
Here, we review clinical and preclinical studies that provide evidence both for and against a causal role for the SCN in mood disorders.
American Psychological Association (APA)
Vadnie, Chelsea A.& McClung, Colleen A.. 2017. Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus. Neural Plasticity،Vol. 2017, no. 2017, pp.1-28.
https://search.emarefa.net/detail/BIM-1192884
Modern Language Association (MLA)
Vadnie, Chelsea A.& McClung, Colleen A.. Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus. Neural Plasticity No. 2017 (2017), pp.1-28.
https://search.emarefa.net/detail/BIM-1192884
American Medical Association (AMA)
Vadnie, Chelsea A.& McClung, Colleen A.. Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-28.
https://search.emarefa.net/detail/BIM-1192884
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192884