Cognitive Pragmatic Rehabilitation Program in Schizophrenia: A Single Case fMRI Study
Joint Authors
Geda, Elisabetta
Duca, Sergio
Costa, Tommaso
Gabbatore, Ilaria
Bosco, Francesca M.
Gastaldo, Luigi
Bara, Bruno G.
Sacco, Katiuscia
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Introduction.
The present study was intended to evaluate the effects of a rehabilitative training, the Cognitive Pragmatic Treatment (CPT), aimed at improving communicative-pragmatic abilities and the related cognitive components, on the cerebral modifications of a single case patient diagnosed with schizophrenia.
Methods.
The patient underwent two functional magnetic resonance imaging (fMRI) sessions, before and after the treatment.
In order to assess brain changes, we calculated the Amplitude of Low Frequency Fluctuation (ALFF) index of the resting-state fMRI signal, which is interpreted as reflecting the intensity of the spontaneous regional activity of the brain.
Behavioural measures of the patient’s communicative performance were also gathered before and after training and at follow-up.
Results.
The patient improved his communicative performance in almost all tests.
Posttraining stronger ALFF signal emerged in the superior, inferior, and medial frontal gyri, as well as the superior temporal gyri.
Conclusions.
Even if based on a single case study, these preliminary results show functional changes at the cerebral level that seem to support the patient’s behavioural improvements.
American Psychological Association (APA)
Gabbatore, Ilaria& Bosco, Francesca M.& Geda, Elisabetta& Gastaldo, Luigi& Duca, Sergio& Costa, Tommaso…[et al.]. 2017. Cognitive Pragmatic Rehabilitation Program in Schizophrenia: A Single Case fMRI Study. Neural Plasticity،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1192889
Modern Language Association (MLA)
Gabbatore, Ilaria…[et al.]. Cognitive Pragmatic Rehabilitation Program in Schizophrenia: A Single Case fMRI Study. Neural Plasticity No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1192889
American Medical Association (AMA)
Gabbatore, Ilaria& Bosco, Francesca M.& Geda, Elisabetta& Gastaldo, Luigi& Duca, Sergio& Costa, Tommaso…[et al.]. Cognitive Pragmatic Rehabilitation Program in Schizophrenia: A Single Case fMRI Study. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1192889
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192889