Enhancing Plasticity of the Central Nervous System: Drugs, Stem Cell Therapy, and Neuro-Implants
Joint Authors
Le Friec, Alice
Salabert, Anne-Sophie
Davoust, Carole
Demain, Boris
Vieu, Christophe
Vaysse, Laurence
Payoux, Pierre
Loubinoux, Isabelle
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Stroke represents the first cause of adult acquired disability.
Spontaneous recovery, dependent on endogenous neurogenesis, allows for limited recovery in 50% of patients who remain functionally dependent despite physiotherapy.
Here, we propose a review of novel drug therapies with strong potential in the clinic.
We will also discuss new avenues of stem cell therapy in patients with a cerebral lesion.
A promising future for the development of efficient drugs to enhance functional recovery after stroke seems evident.
These drugs will have to prove their efficacy also in severely affected patients.
The efficacy of stem cell engraftment has been demonstrated but will have to prove its potential in restoring tissue function for the massive brain lesions that are most debilitating.
New answers may lay in biomaterials, a steadily growing field.
Biomaterials should ideally resemble lesioned brain structures in architecture and must be proven to increase functional reconnections within host tissue before clinical testing.
American Psychological Association (APA)
Le Friec, Alice& Salabert, Anne-Sophie& Davoust, Carole& Demain, Boris& Vieu, Christophe& Vaysse, Laurence…[et al.]. 2017. Enhancing Plasticity of the Central Nervous System: Drugs, Stem Cell Therapy, and Neuro-Implants. Neural Plasticity،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1192917
Modern Language Association (MLA)
Le Friec, Alice…[et al.]. Enhancing Plasticity of the Central Nervous System: Drugs, Stem Cell Therapy, and Neuro-Implants. Neural Plasticity No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1192917
American Medical Association (AMA)
Le Friec, Alice& Salabert, Anne-Sophie& Davoust, Carole& Demain, Boris& Vieu, Christophe& Vaysse, Laurence…[et al.]. Enhancing Plasticity of the Central Nervous System: Drugs, Stem Cell Therapy, and Neuro-Implants. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1192917
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192917