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Pattern Recognition Receptor-Mediated Chronic Inflammation in the Development and Progression of Obesity-Related Metabolic Diseases
Joint Authors
Yu, Lili
Song, Xiangfeng
Yang, Yun
Li, Yanhua
Du, Cancan
Zhao, Weidong
Zhang, Hanxiao
Sun, Aiping
Feng, Zhiwei
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-08
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Obesity-induced chronic inflammation is known to promote the development of many metabolic diseases, especially insulin resistance, type 2 diabetes mellitus, nonalcoholic fatty liver disease, and atherosclerosis.
Pattern recognition receptor-mediated inflammation is an important determinant for the initiation and progression of these metabolic diseases.
Here, we review the major features of the current understanding with respect to obesity-related chronic inflammation in metabolic tissues, focus on Toll-like receptors and nucleotide-binding oligomerization domain-like receptors with an emphasis on how these receptors determine metabolic disease progression, and provide a summary on the development and progress of PRR antagonists for therapeutic intervention.
American Psychological Association (APA)
Yu, Lili& Li, Yanhua& Du, Cancan& Zhao, Weidong& Zhang, Hanxiao& Yang, Yun…[et al.]. 2019. Pattern Recognition Receptor-Mediated Chronic Inflammation in the Development and Progression of Obesity-Related Metabolic Diseases. Mediators of Inflammation،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1192943
Modern Language Association (MLA)
Yu, Lili…[et al.]. Pattern Recognition Receptor-Mediated Chronic Inflammation in the Development and Progression of Obesity-Related Metabolic Diseases. Mediators of Inflammation No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1192943
American Medical Association (AMA)
Yu, Lili& Li, Yanhua& Du, Cancan& Zhao, Weidong& Zhang, Hanxiao& Yang, Yun…[et al.]. Pattern Recognition Receptor-Mediated Chronic Inflammation in the Development and Progression of Obesity-Related Metabolic Diseases. Mediators of Inflammation. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1192943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192943