The Cognitive Neuroplasticity of Reading Recovery following Chronic Stroke: A Representational Similarity Analysis Approach
Joint Authors
Fischer-Baum, Simon
Jang, Ava
Kajander, David
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-08
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Damage to certain left hemisphere regions leads to reading impairments, at least acutely, though some individuals eventually recover reading.
Previous neuroimaging studies have shown a relationship between reading recovery and increases in contralesional and perilesional activation during word reading tasks, relative to controls.
Questions remain about how to interpret these changes in activation.
Do these changes reflect functional take-over, a reorganization of functions in the damaged brain? Or do they reveal compensatory masquerade or the use of alternative neural pathways to reading that are available in both patients and controls? We address these questions by studying a single individual, CH, who has made a partial recovery of reading familiar words following stroke.
We use an fMRI analysis technique, representational similarity analysis (RSA), which allows us to decode cognitive function from distributed patterns of neural activity.
Relative to controls, we find that CH shows a shift from visual to orthographic processing in contralesional regions, with a marginally significant result in perilesional regions as well.
This pattern supports a contralesional reorganization of orthographic processing following stroke.
More generally, these analyses demonstrate how powerful RSA can be for mapping the neural plasticity of language function.
American Psychological Association (APA)
Fischer-Baum, Simon& Jang, Ava& Kajander, David. 2017. The Cognitive Neuroplasticity of Reading Recovery following Chronic Stroke: A Representational Similarity Analysis Approach. Neural Plasticity،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1192945
Modern Language Association (MLA)
Fischer-Baum, Simon…[et al.]. The Cognitive Neuroplasticity of Reading Recovery following Chronic Stroke: A Representational Similarity Analysis Approach. Neural Plasticity No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1192945
American Medical Association (AMA)
Fischer-Baum, Simon& Jang, Ava& Kajander, David. The Cognitive Neuroplasticity of Reading Recovery following Chronic Stroke: A Representational Similarity Analysis Approach. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1192945
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1192945