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Alterations in Cortical Thickness and White Matter Integrity in Mild-to-Moderate Communicating Hydrocephalic School-Aged Children Measured by Whole-Brain Cortical Thickness Mapping and DTI
Joint Authors
Yan, Zhihan
Bai, Guanghui
Zhang, Siyu
Ye, Xinjian
Fu, Yuchuan
Mao, Chuanwan
Wu, Aiqin
Liu, Xiaozheng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Follow-up observation is required for mild-to-moderate hydrocephalic patients because of the potential damage to brain.
However, effects of mild-to-moderate hydrocephalus on gray and white matter remain unclear in vivo.
Using structural MRI and diffusion tensor imaging (DTI), current study compared the cortical thickness and white matter integrity between children with mild-to-moderate communicating hydrocephalus and healthy controls.
The relationships between cortical changes and intelligence quota were also examined in patients.
We found that cortical thickness in the left middle temporal and left rostral middle frontal gyrus was significantly lower in the hydrocephalus group compared with that of controls.
Fractional anisotropy in the right corpus callosum body was significantly lower in the hydrocephalus group compared with that of controls.
In addition, there was no association of cortical thinning or white matter fractional anisotropy with intelligence quota in either group.
Thus, our findings provide clues to that mild-to-moderate hydrocephalus could lead to structural brain deficits especially in the middle temporal and middle frontal gyrus prior to the behavior changes.
American Psychological Association (APA)
Zhang, Siyu& Ye, Xinjian& Bai, Guanghui& Fu, Yuchuan& Mao, Chuanwan& Wu, Aiqin…[et al.]. 2017. Alterations in Cortical Thickness and White Matter Integrity in Mild-to-Moderate Communicating Hydrocephalic School-Aged Children Measured by Whole-Brain Cortical Thickness Mapping and DTI. Neural Plasticity،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1193037
Modern Language Association (MLA)
Zhang, Siyu…[et al.]. Alterations in Cortical Thickness and White Matter Integrity in Mild-to-Moderate Communicating Hydrocephalic School-Aged Children Measured by Whole-Brain Cortical Thickness Mapping and DTI. Neural Plasticity No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1193037
American Medical Association (AMA)
Zhang, Siyu& Ye, Xinjian& Bai, Guanghui& Fu, Yuchuan& Mao, Chuanwan& Wu, Aiqin…[et al.]. Alterations in Cortical Thickness and White Matter Integrity in Mild-to-Moderate Communicating Hydrocephalic School-Aged Children Measured by Whole-Brain Cortical Thickness Mapping and DTI. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1193037
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193037