Novel Immunotherapeutic Approaches for Neuroblastoma and Malignant Melanoma
Joint Authors
Morandi, Fabio
Frassoni, Francesco
Ponzoni, Mirco
Brignole, Chiara
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-30
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Neuroblastoma (NB) and malignant melanoma (MM), tumors of pediatric age and adulthood, respectively, share a common origin, both of them deriving from the neural crest cells.
Although NB and MM have a different behavior, in respect to age of onset, primary tissue involvement and metastatic spread, the prognosis for high stage-affected patients is still poor, in spite of aggressive treatment strategies and the huge amount of new discovered biological knowledge.
For these reasons researchers are continuously attempting to find out new treatment options, which in a near future could be translated to the clinical practice.
In the last two decades, a strong effort has been spent in the field of translational research of immunotherapy which led to satisfactory results.
Indeed, several immunotherapeutic clinical trials have been performed and some of them also resulted beneficial.
Here, we summarize preclinical studies based on immunotherapeutic approaches applied in models of both NB and MM.
American Psychological Association (APA)
Morandi, Fabio& Frassoni, Francesco& Ponzoni, Mirco& Brignole, Chiara. 2018. Novel Immunotherapeutic Approaches for Neuroblastoma and Malignant Melanoma. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1193075
Modern Language Association (MLA)
Morandi, Fabio…[et al.]. Novel Immunotherapeutic Approaches for Neuroblastoma and Malignant Melanoma. Journal of Immunology Research No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1193075
American Medical Association (AMA)
Morandi, Fabio& Frassoni, Francesco& Ponzoni, Mirco& Brignole, Chiara. Novel Immunotherapeutic Approaches for Neuroblastoma and Malignant Melanoma. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1193075
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193075