The Acute Phase Proteins Reaction in Children Suffering from Pseudocroup
Joint Authors
Sobieska, Magdalena
Pucher, Beata
Szydlowski, Jaroslaw
Grzegorowski, Michal
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The aim of the study was to evaluate the inflammatory reaction in children with pseudocroup and compare it with other laryngological diseases according to the available literature data.
The study group included 51 children hospitalized because of pseudocroup.
The measurements of the acute phase proteins (APP), such as C-reactive protein (CRP), alpha-1-antitrypsin (AT), alpha-1-antichymotrypsin (ACT), alpha-1-acid glycoprotein (AGP), ceruloplasmin (Cp), transferrin (Tf), alpha-2-macroglobulin (A2M), and haptoglobin (Hp) were obtained at 3 time points.
The glycosylation profiles of AGP, ACT, and Tf were completed.
An increased AGP level was observed in girls.
The AGP glycosylation revealed the advantage of the W0 variant over the W1 variant.
W1 and W2 were decreased in boys.
W3 emerged in boys.
The Tf concentration and T4 variant were lower compared to the control group.
The A2M level was lower after treatment.
The Hp and AT levels were decreased a few weeks later.
The ACT glycosylation revealed a decrease of the A4 variant in boys.
In conclusion, the inflammatory reaction during pseudocroup was of low intensity.
The APP glycosylation suggested a chronic process.
In a follow-up investigation, no normalization of the parameters was noted, but signs of persistent inflammation were observed.
American Psychological Association (APA)
Pucher, Beata& Sobieska, Magdalena& Grzegorowski, Michal& Szydlowski, Jaroslaw. 2019. The Acute Phase Proteins Reaction in Children Suffering from Pseudocroup. Mediators of Inflammation،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1193099
Modern Language Association (MLA)
Pucher, Beata…[et al.]. The Acute Phase Proteins Reaction in Children Suffering from Pseudocroup. Mediators of Inflammation No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1193099
American Medical Association (AMA)
Pucher, Beata& Sobieska, Magdalena& Grzegorowski, Michal& Szydlowski, Jaroslaw. The Acute Phase Proteins Reaction in Children Suffering from Pseudocroup. Mediators of Inflammation. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1193099
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193099