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Neural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments
Joint Authors
Zhang, Meng-Qi
Li, Rui
Wang, Yi-Qun
Huang, Zhi-Li
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-18
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Depression, which is characterized by a pervasive and persistent low mood and anhedonia, greatly impacts patients, their families, and society.
The associated and recurring sleep disturbances further reduce patient’s quality of life.
However, therapeutic sleep deprivation has been regarded as a rapid and robust antidepressant treatment for several decades, which suggests a complicated role of sleep in development of depression.
Changes in neural plasticity are observed during physiological sleep, therapeutic sleep deprivation, and depression.
This correlation might help us to understand better the mechanism underlying development of depression and the role of sleep.
In this review, we first introduce the structure of sleep and the facilitated neural plasticity caused by physiological sleep.
Then, we introduce sleep disturbances and changes in plasticity in patients with depression.
Finally, the effects and mechanisms of antidepressants and therapeutic sleep deprivation on neural plasticity are discussed.
American Psychological Association (APA)
Zhang, Meng-Qi& Li, Rui& Wang, Yi-Qun& Huang, Zhi-Li. 2017. Neural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments. Neural Plasticity،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1193105
Modern Language Association (MLA)
Zhang, Meng-Qi…[et al.]. Neural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments. Neural Plasticity No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1193105
American Medical Association (AMA)
Zhang, Meng-Qi& Li, Rui& Wang, Yi-Qun& Huang, Zhi-Li. Neural Plasticity Is Involved in Physiological Sleep, Depressive Sleep Disturbances, and Antidepressant Treatments. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1193105
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193105