Botanicals as Modulators of Neuroplasticity: Focus on BDNF
Joint Authors
Calabrese, Francesca
Brivio, Paola
Dell'Agli, Mario
Sangiovanni, Enrico
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-31
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
The involvement of brain-derived neurotrophic factor (BDNF) in different central nervous system (CNS) diseases suggests that this neurotrophin may represent an interesting and reliable therapeutic target.
Accordingly, the search for new compounds, also from natural sources, able to modulate BDNF has been increasingly explored.
The present review considers the literature on the effects of botanicals on BDNF.
Botanicals considered were Bacopa monnieri (L.) Pennell, Coffea arabica L., Crocus sativus L., Eleutherococcus senticosus Maxim., Camellia sinensis (L.) Kuntze (green tea), Ginkgo biloba L., Hypericum perforatum L., Olea europaea L.
(olive oil), Panax ginseng C.A.
Meyer, Rhodiola rosea L., Salvia miltiorrhiza Bunge, Vitis vinifera L., Withania somnifera (L.) Dunal, and Perilla frutescens (L.) Britton.
The effect of the active principles responsible for the efficacy of the extracts is reviewed and discussed as well.
The high number of articles published (more than one hundred manuscripts for 14 botanicals) supports the growing interest in the use of natural products as BDNF modulators.
The studies reported strengthen the hypothesis that botanicals may be considered useful modulators of BDNF in CNS diseases, without high side effects.
Further clinical studies are mandatory to confirm botanicals as preventive agents or as useful adjuvant to the pharmacological treatment.
American Psychological Association (APA)
Sangiovanni, Enrico& Brivio, Paola& Dell'Agli, Mario& Calabrese, Francesca. 2017. Botanicals as Modulators of Neuroplasticity: Focus on BDNF. Neural Plasticity،Vol. 2017, no. 2017, pp.1-19.
https://search.emarefa.net/detail/BIM-1193108
Modern Language Association (MLA)
Sangiovanni, Enrico…[et al.]. Botanicals as Modulators of Neuroplasticity: Focus on BDNF. Neural Plasticity No. 2017 (2017), pp.1-19.
https://search.emarefa.net/detail/BIM-1193108
American Medical Association (AMA)
Sangiovanni, Enrico& Brivio, Paola& Dell'Agli, Mario& Calabrese, Francesca. Botanicals as Modulators of Neuroplasticity: Focus on BDNF. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-19.
https://search.emarefa.net/detail/BIM-1193108
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193108