Neural Energy Supply-Consumption Properties Based on Hodgkin-Huxley Model
Joint Authors
Wang, Yihong
Xu, Xuying
Wang, Rubin
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-16
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Electrical activity is the foundation of the neural system.
Coding theories that describe neural electrical activity by the roles of action potential timing or frequency have been thoroughly studied.
However, an alternative method to study coding questions is the energy method, which is more global and economical.
In this study, we clearly defined and calculated neural energy supply and consumption based on the Hodgkin-Huxley model, during firing action potentials and subthreshold activities using ion-counting and power-integral model.
Furthermore, we analyzed energy properties of each ion channel and found that, under the two circumstances, power synchronization of ion channels and energy utilization ratio have significant differences.
This is particularly true of the energy utilization ratio, which can rise to above 100% during subthreshold activity, revealing an overdraft property of energy use.
These findings demonstrate the distinct status of the energy properties during neuronal firings and subthreshold activities.
Meanwhile, after introducing a synapse energy model, this research can be generalized to energy calculation of a neural network.
This is potentially important for understanding the relationship between dynamical network activities and cognitive behaviors.
American Psychological Association (APA)
Wang, Yihong& Wang, Rubin& Xu, Xuying. 2017. Neural Energy Supply-Consumption Properties Based on Hodgkin-Huxley Model. Neural Plasticity،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1193120
Modern Language Association (MLA)
Wang, Yihong…[et al.]. Neural Energy Supply-Consumption Properties Based on Hodgkin-Huxley Model. Neural Plasticity No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1193120
American Medical Association (AMA)
Wang, Yihong& Wang, Rubin& Xu, Xuying. Neural Energy Supply-Consumption Properties Based on Hodgkin-Huxley Model. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1193120
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193120