Glucose Intake Alters Expression of Neuropeptides Derived from Proopiomelanocortin in the Lateral Hypothalamus and the Nucleus Accumbens in Fructose Preference Rats
Joint Authors
Jiao, Guangfa
Zhang, Guozhong
Wang, Haiying
Zhao, Weilin
Cui, Yanwei
Liu, Yongjing
Gao, Feng
Yuan, Fang
Zhang, Yi
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
To study the neuroendocrine mechanism of sugar preference, we investigated the role of glucose feeding in the regulation of expression levels of neuropeptides derived from proopiomelanocortin (POMC) in the lateral hypothalamus (LH) and nucleus accumbens (NAc) in fructose preference rats.
Fructose preference rats were induced by using the lithium chloride backward conditioning procedure.
The fructose preference was confirmed by the two-bottle test.
The drinking behavior of rats was assessed by the fructose concentration gradient test.
The preference of 10% glucose or 0.1% saccharine was assessed, and the expression levels of neuropeptides derived from POMC in the LH and the NAc in fructose preference rats were measured by Western blot analysis.
Fructose preference rats displayed a greater fructose preference than control rats.
Furthermore, fructose preference rats preferred glucose solution rather than saccharine solution, while control rats preferred saccharine solution rather than glucose solution.
The expression levels of neuropeptides derived from POMC in the LH and the NAc were changed by glucose but not saccharine intake.
In summary, the data suggests that glucose intake increases the expression of neuropeptides derived from POMC in the LH and the NAc in fructose preference rats.
American Psychological Association (APA)
Jiao, Guangfa& Zhang, Guozhong& Wang, Haiying& Zhao, Weilin& Cui, Yanwei& Liu, Yongjing…[et al.]. 2017. Glucose Intake Alters Expression of Neuropeptides Derived from Proopiomelanocortin in the Lateral Hypothalamus and the Nucleus Accumbens in Fructose Preference Rats. Neural Plasticity،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1193155
Modern Language Association (MLA)
Jiao, Guangfa…[et al.]. Glucose Intake Alters Expression of Neuropeptides Derived from Proopiomelanocortin in the Lateral Hypothalamus and the Nucleus Accumbens in Fructose Preference Rats. Neural Plasticity No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1193155
American Medical Association (AMA)
Jiao, Guangfa& Zhang, Guozhong& Wang, Haiying& Zhao, Weilin& Cui, Yanwei& Liu, Yongjing…[et al.]. Glucose Intake Alters Expression of Neuropeptides Derived from Proopiomelanocortin in the Lateral Hypothalamus and the Nucleus Accumbens in Fructose Preference Rats. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1193155
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193155