Transcutaneous Vagus Nerve Stimulation Combined with Robotic Rehabilitation Improves Upper Limb Function after Stroke
Joint Authors
Vincenzo, Di Lazzaro
Zollo, Loredana
Guglielmelli, Eugenio
Capone, Fioravante
Miccinilli, Sandra
Pellegrino, Giovanni
Simonetti, Davide
Florio, Lucia
Ranieri, Federico
Falato, Emma
Di Santo, Alessandro
Pepe, Alessio
Sterzi, Silvia
Bressi, Federica
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The efficacy of standard rehabilitative therapy for improving upper limb functions after stroke is limited; thus, alternative strategies are needed.
Vagus nerve stimulation (VNS) paired with rehabilitation is a promising approach, but the invasiveness of this technique limits its clinical application.
Recently, a noninvasive method to stimulate vagus nerve has been developed.
The aim of the present study was to explore whether noninvasive VNS combined with robotic rehabilitation can enhance upper limb functionality in chronic stroke.
Safety and efficacy of this combination have been assessed within a proof-of-principle, double-blind, semirandomized, sham-controlled trial.
Fourteen patients with either ischemic or haemorrhagic chronic stroke were randomized to robot-assisted therapy associated with real or sham VNS, delivered for 10 working days.
Efficacy was evaluated by change in upper extremity Fugl–Meyer score.
After intervention, there were no adverse events and Fugl–Meyer scores were significantly better in the real group compared to the sham group.
Our pilot study confirms that VNS is feasible in stroke patients and can produce a slight clinical improvement in association to robotic rehabilitation.
Compared to traditional stimulation, noninvasive VNS seems to be safer and more tolerable.
Further studies are needed to confirm the efficacy of this innovative approach.
American Psychological Association (APA)
Capone, Fioravante& Miccinilli, Sandra& Pellegrino, Giovanni& Zollo, Loredana& Simonetti, Davide& Bressi, Federica…[et al.]. 2017. Transcutaneous Vagus Nerve Stimulation Combined with Robotic Rehabilitation Improves Upper Limb Function after Stroke. Neural Plasticity،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1193239
Modern Language Association (MLA)
Capone, Fioravante…[et al.]. Transcutaneous Vagus Nerve Stimulation Combined with Robotic Rehabilitation Improves Upper Limb Function after Stroke. Neural Plasticity No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1193239
American Medical Association (AMA)
Capone, Fioravante& Miccinilli, Sandra& Pellegrino, Giovanni& Zollo, Loredana& Simonetti, Davide& Bressi, Federica…[et al.]. Transcutaneous Vagus Nerve Stimulation Combined with Robotic Rehabilitation Improves Upper Limb Function after Stroke. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1193239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193239