Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders
Joint Authors
Torres, Viviana I.
Vallejo, Daniela
Inestrosa, Nibaldo C.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-25, 25 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-26
Country of Publication
Egypt
No. of Pages
25
Main Subjects
Abstract EN
Synapses are complex structures that allow communication between neurons in the central nervous system.
Studies conducted in vertebrate and invertebrate models have contributed to the knowledge of the function of synaptic proteins.
The functional synapse requires numerous protein complexes with specialized functions that are regulated in space and time to allow synaptic plasticity.
However, their interplay during neuronal development, learning, and memory is poorly understood.
Accumulating evidence links synapse proteins to neurodevelopmental, neuropsychiatric, and neurodegenerative diseases.
In this review, we describe the way in which several proteins that participate in cell adhesion, scaffolding, exocytosis, and neurotransmitter reception from presynaptic and postsynaptic compartments, mainly from excitatory synapses, have been associated with several synaptopathies, and we relate their functions to the disease phenotype.
American Psychological Association (APA)
Torres, Viviana I.& Vallejo, Daniela& Inestrosa, Nibaldo C.. 2017. Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders. Neural Plasticity،Vol. 2017, no. 2017, pp.1-25.
https://search.emarefa.net/detail/BIM-1193241
Modern Language Association (MLA)
Torres, Viviana I.…[et al.]. Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders. Neural Plasticity No. 2017 (2017), pp.1-25.
https://search.emarefa.net/detail/BIM-1193241
American Medical Association (AMA)
Torres, Viviana I.& Vallejo, Daniela& Inestrosa, Nibaldo C.. Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders. Neural Plasticity. 2017. Vol. 2017, no. 2017, pp.1-25.
https://search.emarefa.net/detail/BIM-1193241
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193241