Herbal Compounds Play a Role in Neuroprotection through the Inhibition of Microglial Activation
Joint Authors
Yang, Jian-Mei
Chen, Yongjun
Fu, Yan
Yang, Pin
Zhao, Yang
Xu, Ying
Wang, Xingyu
Li, Kun
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Since microglia possess both neuroprotective and neurotoxic potential, they play a crucial role in the central nervous system (CNS).
Excessive microglial activation induces inflammation-mediated neuronal damage and degeneration.
At present, numerous herbal compounds are able to suppress neurotoxicity via inhibiting microglial activation.
Therefore, many researchers focus on pharmacological inhibitors of microglial activation to ameliorate neurodegenerative disorders.
Further work should concentrate on the exploration of new herbal compounds, which characteristically inhibit microglial neurotoxicity, rather than modulating neuroprotection alone.
In this review, we summarize these herbal compounds, which in the past several years have been shown to exert potential neuroprotective activity by inhibiting microglial activation.
The therapeutic targets and pharmacological mechanisms of these compounds have also been discussed.
American Psychological Association (APA)
Fu, Yan& Yang, Jian-Mei& Wang, Xingyu& Yang, Pin& Zhao, Yang& Li, Kun…[et al.]. 2018. Herbal Compounds Play a Role in Neuroprotection through the Inhibition of Microglial Activation. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1193273
Modern Language Association (MLA)
Fu, Yan…[et al.]. Herbal Compounds Play a Role in Neuroprotection through the Inhibition of Microglial Activation. Journal of Immunology Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1193273
American Medical Association (AMA)
Fu, Yan& Yang, Jian-Mei& Wang, Xingyu& Yang, Pin& Zhao, Yang& Li, Kun…[et al.]. Herbal Compounds Play a Role in Neuroprotection through the Inhibition of Microglial Activation. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1193273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193273