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Viruses Seen by Our Cells: The Role of Viral RNA Sensors
Joint Authors
Said, Elias
Lamarre, Daniel
Tremblay, Nicolas
Al-Balushi, Mohammed S.
al-Jabri, A. A.
Source
Journal of Immunology Research
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-30
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
The role of the innate immune response in detecting RNA viruses is crucial for the establishment of proper inflammatory and antiviral responses.
Different receptors, known as pattern recognition receptors (PRRs), are present in the cytoplasm, endosomes, and on the cellular surface.
These receptors have the capacity to sense the presence of viral nucleic acids as pathogen-associated molecular patterns (PAMPs).
This recognition leads to the induction of type 1 interferons (IFNs) as well as inflammatory cytokines and chemokines.
In this review, we provide an overview of the significant involvement of cellular RNA helicases and Toll-like receptors (TLRs) 3, 7, and 8 in antiviral immune defenses.
American Psychological Association (APA)
Said, Elias& Tremblay, Nicolas& Al-Balushi, Mohammed S.& al-Jabri, A. A.& Lamarre, Daniel. 2018. Viruses Seen by Our Cells: The Role of Viral RNA Sensors. Journal of Immunology Research،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1193309
Modern Language Association (MLA)
Said, Elias…[et al.]. Viruses Seen by Our Cells: The Role of Viral RNA Sensors. Journal of Immunology Research No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1193309
American Medical Association (AMA)
Said, Elias& Tremblay, Nicolas& Al-Balushi, Mohammed S.& al-Jabri, A. A.& Lamarre, Daniel. Viruses Seen by Our Cells: The Role of Viral RNA Sensors. Journal of Immunology Research. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1193309
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193309