Effect of Increased Endometrial Thickness and Implantation Rate by Granulocyte Colony-Stimulating Factor on Unresponsive Thin Endometrium in Fresh In Vitro Fertilization Cycles: A Randomized Clinical Trial
Joint Authors
Sarvi, Fatemeh
Arabahmadi, Marjan
Alleyassin, Ashraf
Aghahosseini, Marzieh
Ghasemi, Marzieh
Source
Obstetrics and Gynecology International
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
The correlation between endometrial thickness and receptivity has been mentioned in various studies.
This study investigated the effect of granulocyte colony-stimulating factor in treating thin endometrium of infertile women who were chosen for in vitro fertilization in our infertility clinic in 2014 and 2015.
Methods.
In this randomized clinical trial, 28 women who were chosen for in vitro fertilization and had endometrial thickness of less than 6 mm on the day of human chorionic gonadotropin (hCG) injection were included in the study.
They were randomly divided into two groups: investigation and control groups.
In investigation group (n=13) one granulocyte colony-stimulating factor vial (300 micrograms in 1 mL) was infused into the uterus within five minutes by embryo transfer catheter.
In control group (n=15) 1 mL of saline was injected into the uterus with the same catheter.
Results.
There were significant differences between the two groups in terms of means of endometrial thickness on oocyte retrieval day (P=0.001), embryo transfer day (P=0.001), hCG injections (P=0.001), and implantation rates (P=0.001).
Conclusion.
Granulocyte colony-stimulating factor can increase endometrial thickness in women treated with in vitro fertilization.
RCT Code is 201406046063N2.
American Psychological Association (APA)
Sarvi, Fatemeh& Arabahmadi, Marjan& Alleyassin, Ashraf& Aghahosseini, Marzieh& Ghasemi, Marzieh. 2017. Effect of Increased Endometrial Thickness and Implantation Rate by Granulocyte Colony-Stimulating Factor on Unresponsive Thin Endometrium in Fresh In Vitro Fertilization Cycles: A Randomized Clinical Trial. Obstetrics and Gynecology International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1193492
Modern Language Association (MLA)
Sarvi, Fatemeh…[et al.]. Effect of Increased Endometrial Thickness and Implantation Rate by Granulocyte Colony-Stimulating Factor on Unresponsive Thin Endometrium in Fresh In Vitro Fertilization Cycles: A Randomized Clinical Trial. Obstetrics and Gynecology International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1193492
American Medical Association (AMA)
Sarvi, Fatemeh& Arabahmadi, Marjan& Alleyassin, Ashraf& Aghahosseini, Marzieh& Ghasemi, Marzieh. Effect of Increased Endometrial Thickness and Implantation Rate by Granulocyte Colony-Stimulating Factor on Unresponsive Thin Endometrium in Fresh In Vitro Fertilization Cycles: A Randomized Clinical Trial. Obstetrics and Gynecology International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1193492
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1193492