Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation
Joint Authors
Miller, Elżbieta
Bijak, Michał
Cichoń, Natalia
Szemraj, Janusz
Śliwiński, Tomasz
Czarny, Piotr
Saluk-Bijak, Joanna
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Nitric oxide (NO) is one of the most important signal molecules, involved in both physiological and pathological processes.
As a neurotransmitter in the central nervous system, NO regulates cerebral blood flow, neurogenesis, and synaptic plasticity.
The aim of our study was to investigate the effect of the extremely low-frequency electromagnetic field (ELF-EMF) on generation and metabolism of NO, as a neurotransmitter, in the rehabilitation of poststroke patients.
Forty-eight patients were divided into two groups: ELF-EMF and non-ELF-EMF.
Both groups underwent the same 4-week rehabilitation program.
Additionally, the ELF-EMF group was exposed to an extremely low-frequency electromagnetic field of 40 Hz, 7 mT, for 15 min/day.
Levels of 3-nitrotyrosine, nitrate/nitrite, and TNFα in plasma samples were measured, and NOS2 expression was determined in whole blood samples.
Functional status was evaluated before and after a series of treatments, using the Activity Daily Living, Geriatric Depression Scale, and Mini-Mental State Examination.
We observed that application of ELF-EMF significantly increased 3-nitrotyrosine and nitrate/nitrite levels, while expression of NOS2 was insignificantly decreased in both groups.
The results also show that ELF-EMF treatments improved functional and mental status.
We conclude that ELF-EMF therapy is capable of promoting recovery in poststroke patients.
American Psychological Association (APA)
Cichoń, Natalia& Czarny, Piotr& Bijak, Michał& Miller, Elżbieta& Śliwiński, Tomasz& Szemraj, Janusz…[et al.]. 2017. Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1194022
Modern Language Association (MLA)
Cichoń, Natalia…[et al.]. Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1194022
American Medical Association (AMA)
Cichoń, Natalia& Czarny, Piotr& Bijak, Michał& Miller, Elżbieta& Śliwiński, Tomasz& Szemraj, Janusz…[et al.]. Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1194022
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1194022