Radical Scavenger Capacity of Jabuticaba Fruit (Myrciaria cauliflora) and Its Biological Effects in Hypertensive Rats
Joint Authors
Lobo de Andrade, Daniela Medeiros
Borges, Leonardo Luiz
Gil, Eric de Souza
Lavorenti Rocha, Matheus
Marcelino, R. I. A.
Valadares, M. C.
Conceição, Edemilson Cardoso da
de Souza, Camila Gabriela
Jordão, Juliana Bahia Reis
Vaz, Boniek Gontijo
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-20
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Jabuticaba is an exotic fruit native to Brazil that has been arousing medicinal interest.
Using chemical (HPLC-PDA, resonance mass spectra, and NMR), electroanalytical (differential pulse voltammetry, radical scavenging assay), and pharmacological (in vivo and in vitro) approaches, we have identified its bioactive compounds and hypotensive effects on hypertensive rats.
The hydroalcoholic extract of jabuticaba (HEJ) presents a great quantity of phenolic compounds, and several molecules with hydroxyl groups present high efficiency as an antioxidant.
The treatment with HEJ (100 and 300 mg/kg/day, for four weeks) presented hypotensive effects on L-NAME-induced hypertensive rats, possibly improving the nitric oxide bioavailability because of its high antioxidant potential.
Furthermore, renal and cardiac hypertrophies were also attenuated after the HEJ treatment.
Moreover, the vascular responses to contractile and dilating agonists were improved with the HEJ treatment, which is also able to induce nitric oxide production in endothelial cells.
American Psychological Association (APA)
de Souza, Camila Gabriela& Lobo de Andrade, Daniela Medeiros& Jordão, Juliana Bahia Reis& Marcelino, R. I. A.& Borges, Leonardo Luiz& Vaz, Boniek Gontijo…[et al.]. 2017. Radical Scavenger Capacity of Jabuticaba Fruit (Myrciaria cauliflora) and Its Biological Effects in Hypertensive Rats. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1194059
Modern Language Association (MLA)
de Souza, Camila Gabriela…[et al.]. Radical Scavenger Capacity of Jabuticaba Fruit (Myrciaria cauliflora) and Its Biological Effects in Hypertensive Rats. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1194059
American Medical Association (AMA)
de Souza, Camila Gabriela& Lobo de Andrade, Daniela Medeiros& Jordão, Juliana Bahia Reis& Marcelino, R. I. A.& Borges, Leonardo Luiz& Vaz, Boniek Gontijo…[et al.]. Radical Scavenger Capacity of Jabuticaba Fruit (Myrciaria cauliflora) and Its Biological Effects in Hypertensive Rats. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1194059
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1194059