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Embedding of Bacterial Cellulose Nanofibers within PHEMA Hydrogel Matrices: Tunable Stiffness Composites with Potential for Biomedical Applications
Joint Authors
Michálek, Jiri
Širc, Jakub
Hobzová, Radka
Hrib, Jakub
Karpushkin, Evgeny
Janouskova, Olga
Gatenholm, Paul
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Bacterial cellulose (BC) and poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogels are both considered as biocompatible materials with potential use in various biomedical applications including cartilage, cardiovascular stent, and soft tissue engineering.
In this work, the “ever-wet” process based on in situ UV radical polymerization of HEMA monomer in BC nanofibrous structure impregnated with HEMA was used, and a series of BC-PHEMA composites was prepared.
The composite structures were characterized by ATR FT-IR spectroscopy, WAXD, SEM, and TEM techniques.
The strategy of using densified BC material of various cellulose fiber contents was applied to improve mechanical properties.
The mechanical properties were tested under tensile, dynamic shear, and relaxation modes.
The final composites contained 1 to 20 wt% of BC; the effect of the reinforcement degree on morphology, swelling capacity, and mechanical properties was investigated.
The biocompatibility test of BC-PHEMA composites was performed using mouse mesenchymal stem cells.
American Psychological Association (APA)
Hobzová, Radka& Hrib, Jakub& Širc, Jakub& Karpushkin, Evgeny& Michálek, Jiri& Janouskova, Olga…[et al.]. 2018. Embedding of Bacterial Cellulose Nanofibers within PHEMA Hydrogel Matrices: Tunable Stiffness Composites with Potential for Biomedical Applications. Journal of Nanomaterials،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1194301
Modern Language Association (MLA)
Hobzová, Radka…[et al.]. Embedding of Bacterial Cellulose Nanofibers within PHEMA Hydrogel Matrices: Tunable Stiffness Composites with Potential for Biomedical Applications. Journal of Nanomaterials No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1194301
American Medical Association (AMA)
Hobzová, Radka& Hrib, Jakub& Širc, Jakub& Karpushkin, Evgeny& Michálek, Jiri& Janouskova, Olga…[et al.]. Embedding of Bacterial Cellulose Nanofibers within PHEMA Hydrogel Matrices: Tunable Stiffness Composites with Potential for Biomedical Applications. Journal of Nanomaterials. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1194301
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1194301