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Ischemic Retinopathies: Oxidative Stress and Inflammation
Joint Authors
Rivera, José Carlos
Dabouz, Rabah
Noueihed, Baraa
Omri, Samy
Tahiri, Houda
Chemtob, Sylvain
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-19
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Ischemic retinopathies (IRs), such as retinopathy of prematurity (ROP), diabetic retinopathy (DR), and (in many cases) age-related macular degeneration (AMD), are ocular disorders characterized by an initial phase of microvascular changes that results in ischemia, followed by a second phase of abnormal neovascularization that may culminate into retinal detachment and blindness.
IRs are complex retinal conditions in which several factors play a key role during the development of the different pathological stages of the disease.
Increasing evidence reveals that oxidative stress and inflammatory processes are important contributors to the pathogenesis of IRs.
Despite the beneficial effects of the photocoagulation and anti-VEGF therapy during neovascularization phase, the need to identify novel targets to prevent initial phases of these ocular pathologies is still needed.
In this review, we provide an update on the involvement of oxidative stress and inflammation in the progression of IRs and address some therapeutic interventions by using antioxidants and anti-inflammatory agents.
American Psychological Association (APA)
Rivera, José Carlos& Dabouz, Rabah& Noueihed, Baraa& Omri, Samy& Tahiri, Houda& Chemtob, Sylvain. 2017. Ischemic Retinopathies: Oxidative Stress and Inflammation. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1194488
Modern Language Association (MLA)
Rivera, José Carlos…[et al.]. Ischemic Retinopathies: Oxidative Stress and Inflammation. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1194488
American Medical Association (AMA)
Rivera, José Carlos& Dabouz, Rabah& Noueihed, Baraa& Omri, Samy& Tahiri, Houda& Chemtob, Sylvain. Ischemic Retinopathies: Oxidative Stress and Inflammation. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1194488
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1194488