The Role of Antioxidant Enzymes in the Ovaries
Joint Authors
Xu, Wenming
Zuo, Tao
Liu, Xing-Hui
Chen, Meng
Wang, Shan
He, Guolin
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-24
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Proper physiological function of the ovaries is very important for the entire female reproductive system and overall health.
Reactive oxygen species (ROS) are generated as by-products during ovarian physiological metabolism, and antioxidants are indicated as factors that can maintain the balance between ROS production and clearance.
A disturbance in this balance can induce pathological consequences in oocyte maturation, ovulation, fertilization, implantation, and embryo development, which can ultimately influence pregnancy outcomes.
However, our understanding of the molecular and cellular mechanisms underlying these physiological and pathological processes is lacking.
This article presents up-to-date findings regarding the effects of antioxidants on the ovaries.
An abundance of evidence has confirmed the various significant roles of these antioxidants in the ovaries.
Some animal models are discussed in this review to demonstrate the harmful consequences that result from mutation or depletion of antioxidant genes or genes related to antioxidant synthesis.
Disruption of antioxidant systems may lead to pathological consequences in women.
Antioxidant supplementation is indicated as a possible strategy for treating reproductive disease and infertility by controlling oxidative stress (OS).
To confirm this, further investigations are required and more antioxidant therapy in humans has to been performed.
American Psychological Association (APA)
Wang, Shan& He, Guolin& Chen, Meng& Zuo, Tao& Xu, Wenming& Liu, Xing-Hui. 2017. The Role of Antioxidant Enzymes in the Ovaries. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1194699
Modern Language Association (MLA)
Wang, Shan…[et al.]. The Role of Antioxidant Enzymes in the Ovaries. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1194699
American Medical Association (AMA)
Wang, Shan& He, Guolin& Chen, Meng& Zuo, Tao& Xu, Wenming& Liu, Xing-Hui. The Role of Antioxidant Enzymes in the Ovaries. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1194699
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1194699