Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review
Joint Authors
Andrade, José Paulo
Carneiro, Ângela M.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world.
In this narrative review, we will summarize the nutritional interventions evaluated in numerous observational studies and a few randomized clinical trials.
The AREDS and AREDS2 studies demonstrated that supplements including vitamins C and E, beta-carotene, and zinc may reduce the progression to advanced AMD, in some patients, by 25% in five years.
This is one of the few nutritional supplements known to have beneficial effects in any eye disease.
Lutein/zeaxanthin supplementation may have beneficial effects in some individuals whereas omega-3 fatty acids supplementation needs to be further investigated and supported by more evidence.
Genetic factors may explain the different patterns of response and explain differences found among individuals.
More importantly, a combination of lifestyle behaviors such as the avoidance of smoking, physical activity, and the adoption of a healthy dietary pattern like the Mediterranean diet was associated with a lower prevalence of AMD.
The adoption of these lifestyles may reduce the prevalence of the early stages of AMD and decrease the number of individuals who develop advanced AMD and consequently the onerous and climbing costs associated with the treatment of this disease.
American Psychological Association (APA)
Carneiro, Ângela M.& Andrade, José Paulo. 2017. Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1195246
Modern Language Association (MLA)
Carneiro, Ângela M.& Andrade, José Paulo. Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1195246
American Medical Association (AMA)
Carneiro, Ângela M.& Andrade, José Paulo. Nutritional and Lifestyle Interventions for Age-Related Macular Degeneration: A Review. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1195246
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195246