Acute Consumption of Bordo Grape Juice and Wine Improves Serum Antioxidant Status in Healthy Individuals and Inhibits Reactive Oxygen Species Production in Human Neuron-Like Cells
Joint Authors
Quatrin, Andréia
Emanuelli, Tatiana
Copetti, Cristiane
Franco, Fernanda Wouters
Machado, Eduarda da Rosa
Soquetta, Marcela Bromberger
Ramos, Vitor de Miranda
Sautter, Cláudia Kaehler
Penna, Neidi Garcia
Fonseca Moreira, José Cláudio
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-01
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Few studies investigated the biological effects of American grape cultivars.
We investigated the metabolic response after acute consumption of grape juice or wine from Bordo grapes (Vitis labrusca) in a placebo-controlled crossover study with fifteen healthy volunteers.
Blood samples were collected 1 hour after the intake of 100 mL of water, juice, or wine to measure TBARS, ABTS, FRAP, glucose, and uric acid levels.
To evaluate differences in cellular response, intracellular reactive species production (DCFH-DA) and metabolic mitochondrial viability (MTT) were assessed after exposure of human neuron-like cells (SH-SY5Y) to juice or wine.
Glycemia was reduced after juice or wine consumption, whereas blood levels of uric acid were reduced after juice consumption but increased after wine consumption.
Juice and wine consumption reduced plasma lipid peroxidation and increased plasma antioxidant capacity (ABTS and FRAP assays).
Furthermore, juice inhibited H2O2-induced intracellular production of reactive species (RS) and increased the viability of SH-SY5Y cells.
In contrast, wine (dealcoholized) exhibited a per se effect by inducing the production of RS and reducing cell viability.
These results indicate a positive impact of acute consumption of Bordo juice and wine on human oxidative status, whereas only juice had protective effects against oxidative stress-induced cytotoxicity.
American Psychological Association (APA)
Copetti, Cristiane& Franco, Fernanda Wouters& Machado, Eduarda da Rosa& Soquetta, Marcela Bromberger& Quatrin, Andréia& Ramos, Vitor de Miranda…[et al.]. 2018. Acute Consumption of Bordo Grape Juice and Wine Improves Serum Antioxidant Status in Healthy Individuals and Inhibits Reactive Oxygen Species Production in Human Neuron-Like Cells. Journal of Nutrition and Metabolism،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1195380
Modern Language Association (MLA)
Copetti, Cristiane…[et al.]. Acute Consumption of Bordo Grape Juice and Wine Improves Serum Antioxidant Status in Healthy Individuals and Inhibits Reactive Oxygen Species Production in Human Neuron-Like Cells. Journal of Nutrition and Metabolism No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1195380
American Medical Association (AMA)
Copetti, Cristiane& Franco, Fernanda Wouters& Machado, Eduarda da Rosa& Soquetta, Marcela Bromberger& Quatrin, Andréia& Ramos, Vitor de Miranda…[et al.]. Acute Consumption of Bordo Grape Juice and Wine Improves Serum Antioxidant Status in Healthy Individuals and Inhibits Reactive Oxygen Species Production in Human Neuron-Like Cells. Journal of Nutrition and Metabolism. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1195380
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195380