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The Crosstalk between ROS and Autophagy in the Field of Transplantation Medicine
Joint Authors
Ottens, Petra J.
Leuvenink, Henri G. D.
Van Erp, Anne C.
Hoeksma, Dane
Rebolledo, Rolando A.
Jochmans, Ina
Monbaliu, Diethard
Pirenne, Jacques
Decuypere, Jean-Paul
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-19
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Many factors during the transplantation process influence posttransplant graft function and survival, including donor type and age, graft preservation methods (cold storage, machine perfusion), and ischemia-reperfusion injury.
Successively, they will lead to cellular and molecular alterations that determine cell and ultimately organ fate.
Oxidative stress and autophagy are implicated in posttransplant outcome since they are both affected by the stress responses triggered in each step (donor, preservation, and recipient) of the transplantation process.
Furthermore, oxidative stress influences autophagy and vice versa.
Interestingly, both processes have positive as well as negative effects on graft outcome, suggesting they are tightly linked during the transplantation process.
In this review, we discuss the importance, regulation and crosstalk of oxidative signals, and autophagy in the field of transplantation medicine.
American Psychological Association (APA)
Van Erp, Anne C.& Hoeksma, Dane& Rebolledo, Rolando A.& Ottens, Petra J.& Jochmans, Ina& Monbaliu, Diethard…[et al.]. 2017. The Crosstalk between ROS and Autophagy in the Field of Transplantation Medicine. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1195455
Modern Language Association (MLA)
Van Erp, Anne C.…[et al.]. The Crosstalk between ROS and Autophagy in the Field of Transplantation Medicine. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1195455
American Medical Association (AMA)
Van Erp, Anne C.& Hoeksma, Dane& Rebolledo, Rolando A.& Ottens, Petra J.& Jochmans, Ina& Monbaliu, Diethard…[et al.]. The Crosstalk between ROS and Autophagy in the Field of Transplantation Medicine. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1195455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195455