The Effects of Krill Oil on mTOR Signaling and Resistance[tnq_nbsp] Exercise: A Pilot Study
Joint Authors
Purpura, Martin
Jäger, Ralf
Georges, John
Sharp, Matthew H.
Lowery, Ryan P.
Wilson, Jacob M.
Hornberger, Troy A.
Harding, Flint
Johnson, James H.
Peele, David M.
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-26
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Introduction.
Krill oil supplementation has been shown to improve postexercise immune function; however, its effect on muscle hypertrophy is currently unknown.
Therefore, the aim of present study was to investigate the ability of krill oil to stimulate mTOR signaling and its ability to augment resistance 3b2:?thyc=10 training-induced3b2:?thyc changes in body composition and performance.
Methods.
C2C12 myoblasts cells were stimulated with krill oil or 3b2:?thyc=10 soy-derived3b2:?thyc phosphatidylcholine (3b2:?thyc=10 S-PC),3b2:?thyc and then, the ratio of P-3b2:?show $132# 3b2:?thyc=10 p70-3893b2:?thyc to total p70 was used as readout for mTOR signaling.
In 3b2:?thyc=10 double-blind,3b2:?thyc 3b2:?thyc=10 placebo-controlled3b2:?thyc study, resistance trained subjects consumed either 3 g krill oil daily or placebo, and each took part in an 8-week periodized resistance training program.
Body composition, maximal strength, peak power, and rate of perceived recovery were assessed collectively at the end of weeks 0 and 8.
In addition, safety parameters (comprehensive metabolic panel (CMP), complete blood count (CBC), and urine analysis (UA)) and cognitive performance were measured pre- and posttesting.
Results.
Krill oil significantly stimulated mTOR signaling in comparison to S-3b2:?show $132# PC and control.
No differences for markers on the CMP, CBC, or UA were observed.
Krill oil significantly increased lean body mass from baseline (p=0.021, 1.4 kg, +2.1%); however, there were no statistically significant differences between groups for any measures taken.
Conclusion.
Krill oil activates mTOR signaling.
Krill oil supplementation in athletes is safe, and its effect on resistance exercise deserves further research.
American Psychological Association (APA)
Georges, John& Sharp, Matthew H.& Lowery, Ryan P.& Wilson, Jacob M.& Purpura, Martin& Hornberger, Troy A.…[et al.]. 2018. The Effects of Krill Oil on mTOR Signaling and Resistance[tnq_nbsp] Exercise: A Pilot Study. Journal of Nutrition and Metabolism،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1195457
Modern Language Association (MLA)
Georges, John…[et al.]. The Effects of Krill Oil on mTOR Signaling and Resistance[tnq_nbsp] Exercise: A Pilot Study. Journal of Nutrition and Metabolism No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1195457
American Medical Association (AMA)
Georges, John& Sharp, Matthew H.& Lowery, Ryan P.& Wilson, Jacob M.& Purpura, Martin& Hornberger, Troy A.…[et al.]. The Effects of Krill Oil on mTOR Signaling and Resistance[tnq_nbsp] Exercise: A Pilot Study. Journal of Nutrition and Metabolism. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1195457
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195457