Bactericidal and Cytotoxic Activities of Polyphenol Extracts from Solanum tuberosum spp. tuberosum and spp. andigena Cultivars on Escherichia coli and Human Neuroblastoma SH-SY5Y Cells In Vitro
Joint Authors
Silveyra, María Ximena
Lanteri, María Luciana
Damiano, Rocío Belén
Andreu, Adriana Balbina
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Potatoes (Solanum tuberosum L.) are a good source of dietary antioxidant polyphenols.
This study investigated the potential antioxidant, bactericidal, and cytotoxic activities in vitro of the phenolic compounds present in tubers of one S.
tuberosum spp.
tuberosum (Summerside), and three S.
tuberosum spp.
andigena (landraces Moradita, Waicha, and Santa María) cultivars.
Both the content of phenolic acids, chlorogenic acids (CGAs) being the most abundant, and the antioxidant activity were higher in extracts from skin than from flesh.
Extracts from Moradita flesh and Summerside skin showed bactericidal activity against Escherichia coli ATCC 25922 but failed to inhibit pathogenic E.
coli O157.
Both extracts lack pigmentation but do contain 5-CGA, caffeic, and ferulic acids.
Positive control with gentamicin and commercial 5-CGA resulted in a complete inhibition of bacterial growth.
In addition, all potato extracts and commercial 5-CGA diminished dose-dependently human neuroblastoma SH-SY5Y cell viability.
Skin extracts were more potent than flesh extracts.
Among flesh extracts, Moradita was the most potent.
Together, our results suggest that Moradita flesh could provide a desirable source of important health-promoting substances.
Findings indicate that the biological activity of potato extracts is a combination of various bioactive compounds and contribute to the revalorization of potato as a functional food.
American Psychological Association (APA)
Silveyra, María Ximena& Lanteri, María Luciana& Damiano, Rocío Belén& Andreu, Adriana Balbina. 2018. Bactericidal and Cytotoxic Activities of Polyphenol Extracts from Solanum tuberosum spp. tuberosum and spp. andigena Cultivars on Escherichia coli and Human Neuroblastoma SH-SY5Y Cells In Vitro. Journal of Nutrition and Metabolism،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1195462
Modern Language Association (MLA)
Silveyra, María Ximena…[et al.]. Bactericidal and Cytotoxic Activities of Polyphenol Extracts from Solanum tuberosum spp. tuberosum and spp. andigena Cultivars on Escherichia coli and Human Neuroblastoma SH-SY5Y Cells In Vitro. Journal of Nutrition and Metabolism No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1195462
American Medical Association (AMA)
Silveyra, María Ximena& Lanteri, María Luciana& Damiano, Rocío Belén& Andreu, Adriana Balbina. Bactericidal and Cytotoxic Activities of Polyphenol Extracts from Solanum tuberosum spp. tuberosum and spp. andigena Cultivars on Escherichia coli and Human Neuroblastoma SH-SY5Y Cells In Vitro. Journal of Nutrition and Metabolism. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1195462
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195462