Relationship between Serum Vitamin D Levels and HDL Cholesterol in Postmenopausal Women from Colombian Caribbean

Abstract EN

Background.

Previous evidence suggests that metabolic disorders in postmenopausal women could be related with low serum vitamin D levels.

For example, vitamin D deficiency has been associated with increased risk factors for cardiovascular disease (CVD), mainly those related with metabolic syndrome.

Objective.

To assess the relationship between the serum vitamin D (25-OH-D) levels and the metabolic syndrome markers in postmenopausal women.

Methods.

This descriptive and cross-sectional study was conducted in 183 postmenopausal women of four municipalities from Colombian Caribbean.

The serum 25-OH-D levels and the anthropometric and biochemical markers were assessed and correlated with metabolic syndrome.

Results.

The average value of serum vitamin D (25-OH-D) was 26.34 ± 9.08 ng/mL, and 69.95% of the women had vitamin D levels <30 ng/mL, of which 43.72% were with insufficiency (<30 to >20 ng/mL) and 26.23% with deficiency (<20 ng/mL).

Of the evaluated women, the 81.42% seemed to have metabolic syndrome.

Through the linear regression, one significant positive association was observed between the HDL cholesterol and the 25-OH-D levels (P=0.014).

Conclusion.

In the evaluated population in this study, vitamin D deficiency is related with low HDL cholesterol levels.