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Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. and Their Chemical Composition
Joint Authors
Skała, Ewa
Wysokińska, Halina
Pytel, Dariusz
Sitarek, Przemysław
Szemraj, Janusz
Toma, Monika
Śliwiński, Tomasz
Białas, Adam Jerzy
Rijo, Patrícia
Garcia, Catarina
Kalemba, Danuta
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-16
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Essential oils obtained from the NR (normal roots) and HR (hairy roots) of the medicinal plant Leonurus sibiricus root were used in this study.
The essential oil compositions were detected by GC-MS.
Eighty-five components were identified in total.
Seventy components were identified for NR essential oil.
The major constituents in NR essential oil were β-selinene (9.9%), selina-4,7-diene (9.7%), (E)-β-caryophyllene (7.3%),myli-4(15)-ene (6.4%), and guaia-1(10),11-diene (5.9%).
Sixty-seven components were identified in HR essential oil, the main constituents being (E)-β-caryophyllene (22.6%), and germacrene D (19.8%).
The essential oils were tested for cytotoxic effect, antimicrobial, anti-inflammatory, and antioxidant activities.
Both essential oils showed activity against grade IV glioma cell lines (IC50 = 400 μg/mL), antimicrobial (MIC and MFC values of 2500 to 125 μg/mL), and anti-inflammatory (decreased level of IL-1β, IL-6, TNF-α, and IFN-γ in LPS-stimulated cells).The essential oils exhibited moderate antioxidant activity in ABTS (EC50 = 98 and 88 μg/mL) assay.
This is the first study to examine composition of the essential oils and their antimicrobial, antioxidant, antiproliferative, and anti-inflammatory activities.
The results indicate that essential oils form L.
sibiricus root may be used in future as an alternative to synthetic antimicrobial agents with potential application in the food and pharmaceutical industries.
American Psychological Association (APA)
Sitarek, Przemysław& Rijo, Patrícia& Garcia, Catarina& Skała, Ewa& Kalemba, Danuta& Białas, Adam Jerzy…[et al.]. 2017. Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. and Their Chemical Composition. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1195612
Modern Language Association (MLA)
Sitarek, Przemysław…[et al.]. Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. and Their Chemical Composition. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1195612
American Medical Association (AMA)
Sitarek, Przemysław& Rijo, Patrícia& Garcia, Catarina& Skała, Ewa& Kalemba, Danuta& Białas, Adam Jerzy…[et al.]. Antibacterial, Anti-Inflammatory, Antioxidant, and Antiproliferative Properties of Essential Oils from Hairy and Normal Roots of Leonurus sibiricus L. and Their Chemical Composition. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1195612
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195612