Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant
Joint Authors
Wang, Ning
Tan, Hor Yue
Li, Sha
Xu, Yu
Guo, Wei
Feng, Yibin
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-26
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Selenium is an essential mineral naturally found in soil, water, and some of the food.
As an antioxidant, it is one of the necessary trace elements in human body and has been suggested as a dietary supplement for health benefit.
Although the human body only needs a trace amount of selenium every day, plenty of recent studies have revealed that selenium is indispensable for maintaining normal functions of metabolism.
In this study, we reviewed the antioxidant role of nutritional supplementation of selenium in the management of major chronic metabolic disorders, including hyperlipidaemia, hyperglycaemia, and hyperphenylalaninemia.
Clinical significance of selenium deficiency in chronic metabolic diseases was elaborated, while clinical and experimental observations of dietary supplementation of selenium in treating chronic metabolic diseases, such as diabetes, arteriosclerosis, and phenylketonuria, were summarized.
Toxicity and recommended dose of selenium were discussed.
The mechanism of action was also proposed via inspecting the interaction of molecular networks and predicting target protein such as xanthine dehydrogenase in various diseases.
Future direction in studying the role of selenium in metabolic disorders was also highlighted.
In conclusion, highlighting the beneficial role of selenium in this review would advance our knowledge of the dietary management of chronic metabolic diseases.
American Psychological Association (APA)
Wang, Ning& Tan, Hor Yue& Li, Sha& Xu, Yu& Guo, Wei& Feng, Yibin. 2017. Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1195684
Modern Language Association (MLA)
Wang, Ning…[et al.]. Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1195684
American Medical Association (AMA)
Wang, Ning& Tan, Hor Yue& Li, Sha& Xu, Yu& Guo, Wei& Feng, Yibin. Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1195684
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195684