Current Role of Chemotherapy in Nonmetastatic Nasopharyngeal Cancer

Abstract EN

Nasopharyngeal carcinoma is highly radio- and chemosensitive tumor with its unique clinical and biological behavior.

Treatment of stage I disease is radical radiotherapy alone.

For stage II disease treatment is radiotherapy with or without chemotherapy.

The standard of care for locally advanced nasopharyngeal cancer (stages III-IVB) is concurrent chemoradiation.

Optimum timing and sequence of chemotherapy are not yet well-defined.

The role of adjuvant and induction chemotherapy is debatable.

Here we are going to highlight the role of chemotherapy in nasopharyngeal carcinoma, its benefit, and controversies regarding timing and sequences.