Resection of Liver Metastases: A Treatment Provides a Long-Term Survival Benefit for Patients with Advanced Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis
Joint Authors
Fu, Deliang
Yu, Xinzhe
Gu, Jichun
Wu, Haoxuan
Li, Ji
Jin, Chen
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
Nonsurgical therapies, including biotherapy, chemotherapy, and liver-directed therapy, provided a limit survival benefit for PNET patients with hepatic metastases.
With the development of liver resection technique, there was a controversy on whether to perform a liver resection for these patients.
Methods.
A computerized search was made of the Medline/PubMed, EMbase, Cochrane Library, and SinoMed (CBM) before March 2018.
A meta-analysis was performed to investigate the differences in the efficacy of liver resection and nonliver resection treatments based on the evaluation of morbidity, 30-day mortality, symptom relief rate, and 1-, 3-, and 5-year survival.
Two investigators reviewed all included articles and extracted the data of them.
The meta-analysis was performed via Review Manager 5.3 software.
Results.
A total of 13 cohort studies with 1524 patients were included in this meta-analysis.
Compared with the nonliver resection group, liver resection group had a longer 1-, 3-, and 5-year survival time and a higher symptom relief with an acceptable mortality and morbidity.
Conclusions.
Liver resection is a safe treatment and could significantly prolong the long-term prognosis for highly selected patients with resectable liver metastases from PNET.
Further randomized, controlled trials are needed.
American Psychological Association (APA)
Yu, Xinzhe& Gu, Jichun& Wu, Haoxuan& Fu, Deliang& Li, Ji& Jin, Chen. 2018. Resection of Liver Metastases: A Treatment Provides a Long-Term Survival Benefit for Patients with Advanced Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis. Journal of Oncology،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1195818
Modern Language Association (MLA)
Yu, Xinzhe…[et al.]. Resection of Liver Metastases: A Treatment Provides a Long-Term Survival Benefit for Patients with Advanced Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis. Journal of Oncology No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1195818
American Medical Association (AMA)
Yu, Xinzhe& Gu, Jichun& Wu, Haoxuan& Fu, Deliang& Li, Ji& Jin, Chen. Resection of Liver Metastases: A Treatment Provides a Long-Term Survival Benefit for Patients with Advanced Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis. Journal of Oncology. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1195818
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195818