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Contribution and Interactions of Hydroxycinnamic Acids Found in Bran and Wholegrain Sorghum (Sorghum bicolor L. Moench): Effects on the Antioxidant Capacity and Inhibition of Human Erythrocyte Hemolysis
Joint Authors
González Aguilar, Gustavo A.
Robles Sánchez, Maribel
Salazar Lopez, Norma Julieta
Loarca-Piña, Guadalupe
Cinco-Moroyoqui, Francisco J.
Rouzaud-Sández, Ofelia
Domínguez-Avila, J. Abraham
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
An imbalance between free radicals and antioxidants is known as oxidative stress, and it promotes cellular aging and the development of chronic noncommunicable diseases.
The bioactive compounds present in food play an important role in preventing oxidative stress.
The aim of this study was to determine the contributions and interactions of the hydroxycinnamic acids found in the bran and whole grain of sorghum and to evaluate their effects on the antioxidant capacity and inhibition of the hemolysis of human erythrocytes.
Results showed that the caffeic acid, p-coumaric acid, and ferulic acid found in sorghum contributed to the scavenging of DPPH and ABTS radicals in various proportions.
Ferulic acid, which was present in bound form in the bran and wholegrain sorghum, significantly inhibited the AAPH radical-induced oxidation of the erythrocyte membranes by 78.0 and 4.3%, respectively.
Combinations of two, three, or four hydroxycinnamic acids may interact in an antagonistic or synergistic manner, thereby altering each other’s bioactivities.
The various interactions between the different sorghum bioactives can have a significant impact on their potential bioactivities.
These results can be useful in the design of functional foods that aim to deliver bioactives to mitigate cellular aging or noncommunicable diseases.
American Psychological Association (APA)
Salazar Lopez, Norma Julieta& González Aguilar, Gustavo A.& Loarca-Piña, Guadalupe& Cinco-Moroyoqui, Francisco J.& Rouzaud-Sández, Ofelia& Domínguez-Avila, J. Abraham…[et al.]. 2017. Contribution and Interactions of Hydroxycinnamic Acids Found in Bran and Wholegrain Sorghum (Sorghum bicolor L. Moench): Effects on the Antioxidant Capacity and Inhibition of Human Erythrocyte Hemolysis. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1195958
Modern Language Association (MLA)
Salazar Lopez, Norma Julieta…[et al.]. Contribution and Interactions of Hydroxycinnamic Acids Found in Bran and Wholegrain Sorghum (Sorghum bicolor L. Moench): Effects on the Antioxidant Capacity and Inhibition of Human Erythrocyte Hemolysis. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1195958
American Medical Association (AMA)
Salazar Lopez, Norma Julieta& González Aguilar, Gustavo A.& Loarca-Piña, Guadalupe& Cinco-Moroyoqui, Francisco J.& Rouzaud-Sández, Ofelia& Domínguez-Avila, J. Abraham…[et al.]. Contribution and Interactions of Hydroxycinnamic Acids Found in Bran and Wholegrain Sorghum (Sorghum bicolor L. Moench): Effects on the Antioxidant Capacity and Inhibition of Human Erythrocyte Hemolysis. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1195958
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195958