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The Effect of On-Pump and Off-Pump Bypass Operations on Oxidative Damage and Antioxidant Parameters
Joint Authors
Türker, Fevzi Sarper
Doğan, Ayşe
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
The aim of the study is to determine the oxidative status in on-pump and off-pump coronary artery surgery and contribute to possible surgical choices in clinical practices in accordance with the information obtained as a result of this study.
Methods.
52 patients undergoing open heart surgery (26 patients in on-pump group and 26 patients in off-pump group) were included in the study.
MDA, GPx, GSH, CAT, and SOD were investigated in blood samples.
Results.
In the on-pump group, it was determined that there were a significant increase in MDA level in the peroperative period compared to the preoperative and postoperative periods and a significant increase in GSH level in the postoperative period than in the preoperative period.
Additionally, while there was a significant decrease in CAT activity in the postoperative period than in the peroperative period, there was a statistically significant increase in SOD enzyme activity in the postoperative period compared to the preoperative and peroperative periods.
A statistically significant increase was observed in SOD enzyme activity in the postoperative period in on-pump compared to off-pump group.
Conclusion.
It is thought that this oxidative damage can be suppressed by administering a suitable antioxidant supplement in the preoperative and peroperative periods among patients undergoing the on-pump operation.
American Psychological Association (APA)
Doğan, Ayşe& Türker, Fevzi Sarper. 2017. The Effect of On-Pump and Off-Pump Bypass Operations on Oxidative Damage and Antioxidant Parameters. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1195981
Modern Language Association (MLA)
Doğan, Ayşe& Türker, Fevzi Sarper. The Effect of On-Pump and Off-Pump Bypass Operations on Oxidative Damage and Antioxidant Parameters. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1195981
American Medical Association (AMA)
Doğan, Ayşe& Türker, Fevzi Sarper. The Effect of On-Pump and Off-Pump Bypass Operations on Oxidative Damage and Antioxidant Parameters. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1195981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1195981