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Oxidative Stress: Harms and Benefits for Human Health
Joint Authors
Bitto, Alessandra
Cucinotta, Mariapaola
Pizzino, Gabriele
Irrera, Natasha
Pallio, Giovanni
Arcoraci, Vincenzo
Mannino, Federica
Squadrito, Francesco
Altavilla, Domenica
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-27
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Oxidative stress is a phenomenon caused by an imbalance between production and accumulation of oxygen reactive species (ROS) in cells and tissues and the ability of a biological system to detoxify these reactive products.
ROS can play, and in fact they do it, several physiological roles (i.e., cell signaling), and they are normally generated as by-products of oxygen metabolism; despite this, environmental stressors (i.e., UV, ionizing radiations, pollutants, and heavy metals) and xenobiotics (i.e., antiblastic drugs) contribute to greatly increase ROS production, therefore causing the imbalance that leads to cell and tissue damage (oxidative stress).
Several antioxidants have been exploited in recent years for their actual or supposed beneficial effect against oxidative stress, such as vitamin E, flavonoids, and polyphenols.
While we tend to describe oxidative stress just as harmful for human body, it is true as well that it is exploited as a therapeutic approach to treat clinical conditions such as cancer, with a certain degree of clinical success.
In this review, we will describe the most recent findings in the oxidative stress field, highlighting both its bad and good sides for human health.
American Psychological Association (APA)
Pizzino, Gabriele& Irrera, Natasha& Cucinotta, Mariapaola& Pallio, Giovanni& Mannino, Federica& Arcoraci, Vincenzo…[et al.]. 2017. Oxidative Stress: Harms and Benefits for Human Health. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1196083
Modern Language Association (MLA)
Pizzino, Gabriele…[et al.]. Oxidative Stress: Harms and Benefits for Human Health. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1196083
American Medical Association (AMA)
Pizzino, Gabriele& Irrera, Natasha& Cucinotta, Mariapaola& Pallio, Giovanni& Mannino, Federica& Arcoraci, Vincenzo…[et al.]. Oxidative Stress: Harms and Benefits for Human Health. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1196083
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196083