Assessment of Ocular Surface Damage during the Course of Type 2 Diabetes Mellitus
Joint Authors
Liu, Yan
Fu, Yao
He, Fang-lin
Zhao, Zhanlin
Lu, Linna
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To investigate the impact of disease duration on the ocular surface during the course of type 2 diabetes mellitus compared with nondiabetic controls.
Methods.
One hundred twenty diabetic patients were divided into three groups according to disease duration: less than 5 years, 5–10 years, and over 10 years.
All eyes were imaged using a corneal topographer (Oculus Keratograph 5M).
Tear film measurements and meibography were also recorded.
Meibomian gland changes were scored from 0 to 6 (meiboscore).
Results.
The noninvasive breakup time first (NIKBUT-1st) and noninvasive breakup time average (NIKBUT-avg) were significantly shorter in the over 10 years diabetic group compared with the control group (P=0.0056 and P=0.010, resp.).
Tear meniscus height (TMH) was significantly lower in the over 10 years diabetic group compared with the control group (P=0.0016) and the 5 years group (P=0.0061).
We also found that more patients in the over 10 years diabetic group showed bulbar and limbal hyperemia compared with the control group (bulbar hyperemia: P=0.049; limbal hyperemia: P=0.026).
The meiboscore in the over 10 years diabetic group was significantly higher compared with the other three groups (P<0.05).
Bulbar hyperemia showed a significant negative correlation with NIKBUT-1st in the over 10 years diabetic group (r=−0.35 and P<0.05).
Conclusion.
Ocular surface damage in long-term type 2 diabetes is more severe than that in patients with shorter disease duration.
American Psychological Association (APA)
He, Fang-lin& Zhao, Zhanlin& Liu, Yan& Lu, Linna& Fu, Yao. 2018. Assessment of Ocular Surface Damage during the Course of Type 2 Diabetes Mellitus. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196138
Modern Language Association (MLA)
He, Fang-lin…[et al.]. Assessment of Ocular Surface Damage during the Course of Type 2 Diabetes Mellitus. Journal of Ophthalmology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1196138
American Medical Association (AMA)
He, Fang-lin& Zhao, Zhanlin& Liu, Yan& Lu, Linna& Fu, Yao. Assessment of Ocular Surface Damage during the Course of Type 2 Diabetes Mellitus. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1196138
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196138