The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy
Joint Authors
Aizawa, Naoko
Nakazawa, Toru
Katagiri, Hideki
Hashimoto, Kazuki
Ito, Azusa
Yasuda, Masayuki
Sawada, Shojiro
Kondo, Keiichi
Satake, Chihiro
Kunikata, Hiroshi
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
Nerve conduction velocity (NCV) is an indicator of neuronal damage in the distal segment of the peripheral nerves.
Here, we determined the association between NCV and other systemic and ocular clinical findings, in type 2 diabetes patients with early diabetic retinopathy (DR).
Methods.
This study included 42 eyes of 42 type 2 diabetes patients (median age: 54 years) with no DR or with mild nonproliferative DR.
Standard statistical techniques were used to determine associations between clinical findings.
Results.
Sural sensory conduction velocity (SCV) and tibial motor conduction velocity (MCV) were significantly lower in mild nonproliferative DR patients than patients with no DR (P=0.008 and P=0.01, resp.).
Furthermore, logistic regression analyses revealed that sural SCV and tibial MCV were independent factors contributing to the presence of mild nonproliferative DR (OR 0.83, P=0.012 and OR 0.69 P=0.02, resp.).
Tibial MCV was correlated with choroidal thickness (CT) (P=0.01), and a multiple regression analysis revealed that age, tibial MCV, and carotid intima-media thickness were independent associating factors with CT (P=0.035, P=0.015, and P=0.008, resp.).
Conclusions.
Our findings suggest that reduced NCV may be closely associated with early DR in type 2 diabetes patients.
Thus, reduced nerve conduction is a potential early biomarker of DR.
American Psychological Association (APA)
Ito, Azusa& Kunikata, Hiroshi& Yasuda, Masayuki& Sawada, Shojiro& Kondo, Keiichi& Satake, Chihiro…[et al.]. 2018. The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy. Journal of Ophthalmology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1196271
Modern Language Association (MLA)
Ito, Azusa…[et al.]. The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy. Journal of Ophthalmology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1196271
American Medical Association (AMA)
Ito, Azusa& Kunikata, Hiroshi& Yasuda, Masayuki& Sawada, Shojiro& Kondo, Keiichi& Satake, Chihiro…[et al.]. The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy. Journal of Ophthalmology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1196271
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196271