Epigenetics and Oxidative Stress in Aging
Joint Authors
Guillaumet-Adkins, Amy
Yañez, Yania
Peris-Diaz, Manuel D.
Calabria, Ines
Palanca-Ballester, Cora
Sandoval, Juan
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aging is a multifactorial process characterized by the progressive loss of physiological functions, leading to an increased vulnerability to age-associated diseases and finally to death.
Several theories have been proposed to explain the nature of aging.
One of the most known identifies the free radicals produced by the mitochondrial metabolism as the cause of cellular and DNA damage.
However, there are also several evidences supporting that epigenetic modifications, such as DNA methylation, noncoding RNAs, and histone modifications, play a critical role in the molecular mechanism of aging.
In this review, we explore the significance of these findings and argue how the interlinked effects of oxidative stress and epigenetics can explain the cause of age-related declines.
American Psychological Association (APA)
Guillaumet-Adkins, Amy& Yañez, Yania& Peris-Diaz, Manuel D.& Calabria, Ines& Palanca-Ballester, Cora& Sandoval, Juan. 2017. Epigenetics and Oxidative Stress in Aging. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1196372
Modern Language Association (MLA)
Guillaumet-Adkins, Amy…[et al.]. Epigenetics and Oxidative Stress in Aging. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1196372
American Medical Association (AMA)
Guillaumet-Adkins, Amy& Yañez, Yania& Peris-Diaz, Manuel D.& Calabria, Ines& Palanca-Ballester, Cora& Sandoval, Juan. Epigenetics and Oxidative Stress in Aging. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1196372
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196372