Influence of Synbiotics on Selected Oxidative Stress Parameters

Abstract EN

The aim of the present study was to assess synbiotic (Lactobacillus casei + inulin) influence on oxidative stress parameters such as concentrations of malondialdehyde (MDA), hydrogen peroxide (H2O2), glutathione, and free sulfhydryl groups content.

Experiments were carried out on healthy volunteers (n=32).

The subjects were divided into women group (n=16) and men group (n=16) and randomly assigned to synbiotic and control groups.

Blood samples were collected before synbiotic supplementation and after 7 wks, at the end of the study.

The administration of synbiotic resulted in a significant decrease in MDA (p<0.01), H2O2 (p<0.01), and GSSG concentrations (p<0.05) as compared with the control groups and significant increase in the concentrations of GSHt (p<0.001), GSH (p<0.01), and -SH group content (p<0.05) versus control.

Synbiotics containing L.

casei plus inulin may have positive influence on selected oxidative stress markers.