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UPLC-MSMS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families
Joint Authors
Stochmal, Anna
Pecio, Łukasz
Załuski, Daniel
Bogucka-Kocka, Anna
Och, Anna
Szewczyk, Katarzyna
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Cancer is one of the most occurring diseases in developed and developing countries.
Plant-based compounds are still researched for their anticancer activity and for their quantity in plants.
Therefore, the modern chromatographic methods are applied to quantify them in plants, for example, UPLC-MS/MS (ultraperformance liquid chromatography tandem mass spectrometry).
Therefore, the aim of the present study was to evaluate the content of sanguinarine, berberine, protopine, and chelidonine in Dicentra spectabilis (L.) Lem., Fumaria officinalis L., Glaucium flavum Crantz, Corydalis cava L., Berberis thunbergii DC., Meconopsis cambrica (L.) Vig., Mahonia aquifolium (Pursh) Nutt., Macleaya cordata Willd., and Chelidonium majus L.
For the first time, N,N-dimethyl-hernovine was identified in M.
cambrica, B.
thunbergii, M.
aquifolium, C.
cava, G.
flavum, and C.
majus; methyl-hernovine was identified in G.
flavum; columbamine was identified in B.
thunbergii; and methyl-corypalmine, chelidonine, and sanguinarine were identified in F.
officinalis L.
The richest source of protopine among all the examined species was M.
cordata (5463.64 ± 26.3 μg/g).
The highest amounts of chelidonine and sanguinarine were found in C.
majus (51,040.0 ± 1.8 μg/g and 7925.8 ± 3.3 μg/g, resp.), while B.
thunbergi contained the highest amount of berberine (6358.4 ± 4.2 μg/g).
American Psychological Association (APA)
Och, Anna& Szewczyk, Katarzyna& Pecio, Łukasz& Stochmal, Anna& Załuski, Daniel& Bogucka-Kocka, Anna. 2017. UPLC-MSMS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families. Oxidative Medicine and Cellular Longevity،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1196498
Modern Language Association (MLA)
Och, Anna…[et al.]. UPLC-MSMS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families. Oxidative Medicine and Cellular Longevity No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1196498
American Medical Association (AMA)
Och, Anna& Szewczyk, Katarzyna& Pecio, Łukasz& Stochmal, Anna& Załuski, Daniel& Bogucka-Kocka, Anna. UPLC-MSMS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families. Oxidative Medicine and Cellular Longevity. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1196498
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1196498